Ganglioside GM2 asialo (asialo- GM2; Item No. 24629) is a glycosphingolipid containing three monosaccharide residues and a fatty acid of variable chain length but lacking the sialic acid residue present on ganglioside M2. Asialo-GM2 levels are low-to-undetectable in normal human brain, but it accumulates in the brain of patients with Tay-Sachs and Sandhoff disease, which are neurodegenerative disorders characterized by deficiency of lysosomal β-hexosaminidase A and B, respectively.1 It also binds to various bacteria, including Pseudomonas isolates derived from cystic fibrosis patients.2 Ganglioside GM2 Asialo Polyclonal Antibody can be used for ELISA and TLC immunoblotting. [Matreya, LLC. Catalog No. 1951]WARNING This product is not for human or veterinary use.