For immunochemical detection of p53 (Phospho-Ser392) 1 ea

$345.00

Affinity-purified pure For immunochemical detection of p53 (Phospho-Ser392) 1 ea

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Description

4-hydroxy Nonenal is a lipid peroxidation product derived from oxidized ω-6 polyunsaturated fatty acids such as arachidonic acid and linoleic acid.1,2 It exhibits various biological activities such as cytotoxicity, growth inhibiting activity, genotoxicity, and chemotactic activity and has been widely used as a marker of lipid peroxidation.1,2,3 4-oxo-2-Nonenal is a more recently identified product of lipid peroxidation.4,5,6 It actively modifies histidine and lysine residues on proteins and causes protein cross-linking.7,8 4-oxo-2-Nonenal also modifies 2′-deoxyguanosine, further implicating lipid peroxidation in mutagenesis and carcinogenesis.4WARNING This product is not for human or veterinary use.

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