Product Description

2,4-Dinitrophenol (DNP) is a hapten that induces a strong immune response when attached to proteins or peptides.1,2 DNP can be incorporated at protein carbonyls via covalent linkage of DNP to carbonyl groups using 2,4-dinitrophenylhydrazine (DNPH) or through site-specific incorporation of unnatural amino acids that contain a DNP functional group.3,1 Immunization with DNP-modified proteins or tumor cells induces antibody formation in vivo and has been used in the design of vaccines for clearance of disease-causing cells or viruses and induction of autoimmune diseases such as colitis and thyroiditis in various animal models.4,5 Cayman’s Anti-DNP Monoclonal Antibody can be used for ELISA, Western blot, and immunoprecipitation applications.WARNING This product is not for human or veterinary use.