For immunochemical analysis of CD34 1 ea


For immunochemical analysis of CD34 1 ea



Ribonucleotide reductase, the rate-limiting enzyme for de novo DNA synthesis, is a common target for chemotherapy. Its increased activity in cancer cells is associated with malignant transformation and proliferation.1 Trimidox is a specific ribonucleotide reductase inhibitor that reduces levels of dGTP and dCTP in HL-60 cells, inducing apoptosis via activation of caspases without altering the cell cycle distribution.1,2 Trimidox inhibits growth of human promyelocytic leukemia HL-60 cells with an IC50 value of 35 µM.1WARNING This product is not for human or veterinary use.


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