For fluorescent analysis of SIRT3 96 wells


For fluorescent analysis of SIRT3 96 wells



Protein kinase A (PKA) regulates multiple signal transduction events via protein phosphorylation and is integral to all cellular responses involving the cyclic AMP second messenger system. H-89 is a potent, cell permeable inhibitor of PKA that demonstrates an IC50 value of 0.14 µM and a Ki value of 48 nM in standard kinase assays.1,2 While widely used to disrupt PKA signaling, the inhibitory activity of H-89 is non-selective. H-89 also inhibits S6K1, MSK1, ROCK-II, PKBα, and MAPKAP-K1b with IC50 values of 0.08, 0.12, 0.27, 2.6, and 2.8 µM, respectively.1WARNING This product is not for human or veterinary use.


There are no reviews yet.

Be the first to review “For fluorescent analysis of SIRT3 96 wells”

Your email address will not be published. Required fields are marked *

Got something to discuss?