Complete drug discovery assay for screening COX-1 and COX-2 inhibitors 96 wells

Description

Catechin is a polyphenolic flavonoid which has been isolated from a variety of natural sources including tea leaves, grape seeds, and the wood and bark of trees such as acacia and mahogany. Catechin is a more potent antioxidant than ascorbate or α-tocopherol in certain in vitro assays of lipid peroxidation.1 Catechin inhibits the free radical-induced oxidation of isolated LDL by AAPH.2 It has also been reported to act as an inhibitor of COX-1 with an IC50 of about 80 µM.3 Catechin and other related procyanidin compounds have antitumor activity when tested in a two-stage mouse epidermal carcinoma model employing topical application.1WARNING This product is not for human or veterinary use.