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HomeCancerAn internal standard for the quantification of cim ...

An internal standard for the quantification of cimetidine 1 mg

$319.00

≥99% deuterated forms (d1-d3) pure An internal standard for the quantification of cimetidine 1 mg

Category: Cancer
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Product Description

TMCB is a dual inhibitor of casein kinase 2 (CK2) and ERK8 (IC50 = 0.5 µM for both).1 It also binds to Pim-1, HIPK2, and DYRK1A (Kis = 8.65, 15.25, and 11.9 µM, respectively) and inhibits greater than 50% of the activity of five kinases, including CK2, ERK8, and DYRK2, in a panel of 78 kinases at 10 µM. TMCB induces apoptosis in Jurkat cells when used at concentrations ranging from 10 to 50 µM.WARNING This product is not for human or veterinary use.

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