Active, human recombinant enzyme 1 ea


Active, human recombinant enzyme 1 ea



2,3-DCPE is a proapoptotic compound with selectivity for cancer cells versus normal human cells. It induces apoptosis in vitro in various cancer cell lines (IC50s = 0.89-2.69 µM) more effectively than in normal human fibroblasts (IC50 = 12.6 µM). 2,3-DCPE down-regulates Bcl-xL, however forced overexpression of Bcl-xL is sufficient to block 2,3-DCPE apoptosis induction.1 2,3-DCPE can induce S-phase arrest, upregulate p21, and activate ERK.2WARNING This product is not for human or veterinary use.


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