Product Description

4-Hydroxyphenylacetic acid is a phenolic acid with anti-inflammatory activity.1 It is formed via microbial metabolism of aromatic amino acids and polyphenolic compounds, including flavonoid glycosides, by gut microbiota.2,3,4 4-Hydroxyphenylacetic acid (100 mg/kg) inhibits seawater instillation-induced increases in TNF-α, IL-1β, and IL-6 levels in lung tissue and white blood cell numbers in bronchoalveolar lavage fluid (BALF) and prevents lung edema in a rat model of acute lung injury.1 Levels of 4-hydroxyphenylacetic acid are increased and decreased in serum and urine, respectively, in rats fed a high-fat diet.2 Serum levels of 4-hydroxyphenylacetic acid are increased in patients with stage III pancreatic cancer.5WARNING This product is not for human or veterinary use.