Product Description

Plantamajoside is a phenylethanoid that has been found in P. lanceolata and has diverse biological activities, including antioxidative, anticancer, and anti-inflammatory properties.1,2,3 It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805) radicals in a cell-free assay (IC50 = 11.8 µM). It also inhibits 5-lipoxygenase (5-LO) and 15-LO (IC50s = 0.375 and 96 µM, respectively).1,2 Plantamajoside decreases viability of TE-1 esophageal squamous cell carcinoma (ESCC) cells when used at concentrations ranging from 20 to 320 µg/ml, as well as inhibits LPS-induced epithelial-to-mesenchymal transition (EMT) in Eca-109 and TE-1 cells and decreases phosphorylated NF-κB levels in TE-1 cells.3 Plantamajoside (3 mg/ear) inhibits mouse ear edema induced by arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607) by 25%.1WARNING This product is not for human or veterinary use.