A natural non-caloric sweetener 1 mg

Description

Varlitinib is an inhibitor of EGFR and HER2 (IC50s = 7 and 2 nM, respectively).1,2 It inhibits cell proliferation (IC50s = <20 μM) and induces apoptosis in MDA-MB-453 and MDA-MB-468 triple-negative breast cancer (TNBC) cells.2 Varlitinib inhibits migration, invasion, and mammosphere formation of MDA-MB-231 and MDA-MB-468 cells. In vivo, varlitinib (100 mg/kg) inhibits phosphorylation of EGFR and ERK and reduces tumor weight in an MDA-MB-468 mouse xenograft model.WARNING This product is not for human or veterinary use.