Product Description

Deacetylanisomycin is a derivative of the protein and DNA synthesis inhibitor anisomycin (Item No. 11308) with antimalarial and anticancer activity.1,2 It inhibits the growth of the P. falciparum strains K1 and T9-96 in vitro (IC50s = 40.29 and 33.57 μM, respectively).1 Deacetylanisomycin is cytotoxic to LU99 lung carcinoma and MCF-7 breast cancer cells (IC50s = 23 and 34 μM, respectively). It has been used as a negative control for assessment of protein synthesis inhibitor activity in molluscan neurons.3WARNING This product is not for human or veterinary use.