Description
SPHK 1 catalyzes the phosphorylation of sphingosine to sphingosine-1-phosphate. This reaction plays an important role in determining cell proliferation versus cell death.1,2 SPHK 1 is found in a wide variety of tissues and cell types including kidney, liver, spleen, heart, platelets, and human tumors. On a cellular level, it is found in the cytosolic and membrane fractions.3 Based on the amino acid sequence, this protein has a molecular weight of approximately 43 kDa. The observed band at 50 kDa may be explained by some reported post translational modifications.4WARNING This product is not for human or veterinary use.
Reviews
There are no reviews yet.