Peonidin 3-O-glucoside is a metabolite of cyanidin 3-glucoside (Item No. 16406) and an anthocyanin that has been found in red wine extracts and has diverse biological activities, including antioxidant, anti-inflammatory, antiproliferative, and anti-metastatic properties.1,2,3,4,5 Peonidin 3-O-glucoside scavenges 2,2-diphenyl 1-picylhydrazyl (DPPH; Item No. 14805) and ABTS (Item No. 27317) radicals in cell-free assays (EC50s = 757 and 98 μM, respectively).2 It inhibits IL-1β-induced phosphorylation of IKKα, IκBα, and ERK in human articular chondrocytes when used at a concentration of 2.5 μM.3 Peonidin 3-O-glucoside inhibits the growth of Hs578T human breast cancer cells
in vitro in a concentration-dependent manner and decreases pulmonary metastasis in a mouse model of Lewis lung carcinoma when administered at a dose of 20 mg/kg.4,5
WARNING This product is not for human or veterinary use.