A tryptanthrin derivative with diverse biological activities 1 mg

$6,200.00

≥98% pure A tryptanthrin derivative with diverse biological activities 1 mg

Category:

Description

Balaglitazone is a partial agonist of peroxisome proliferator-activated receptor γ (PPARγ; EC50 = 1.351 μM in a transactivation assay).1 It decreases non-fasting plasma glucose levels in diabetic db/db mice (ED90 = 3 mg/kg per day). Balaglitazone (5 and 10 mg/kg per day) decreases plasma levels of insulin and glucose in an oral glucose tolerance test in diet-induced obese rats.2 In doxorubicin-resistant K562 human myelogenous leukemia cells, balaglitazone (25 μM) decreases P-glycoprotein (P-gp) levels, increases intracellular accumulation of the P-gp substrate rhodamine 123 (Item No. 16672), and sensitizes cells to doxorubicin (Item No. 15007).3WARNING This product is not for human or veterinary use.

Reviews

There are no reviews yet.

Be the first to review “A tryptanthrin derivative with diverse biological activities 1 mg”

Your email address will not be published.

Got something to discuss?


 

Add to cart