A dual inhibitor of EGFR and HER2 5 mg

$12,400.00

≥98% pure A dual inhibitor of EGFR and HER2 5 mg

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Description

Nicotinamide N-oxide is a metabolite of nicotinamide (Item No. 11127).1 It is formed via oxidation of nicotinamide by the cytochrome P450 (CYP) isoform CYP2E1. Nicotinamide N-oxide (30 mM) inhibits proliferation and induces reduction of nitroblue tetrazolium (NBT; Item No. 17341), indicating cell differentiation, in HL-60 promyelocytic leukemia cells.2 Urine levels of nicotinamide N-oxide are elevated in a mouse model of high-fat diet-induced obesity.3WARNING This product is not for human or veterinary use.

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